(University of Vermont; PI: Teresa Leyro, Ph.D.; Mentor: Michael Zvolensky, Ph.D.): This NIDA funded project (NRSA: 1F31 DA024919-01) examined the interaction between PD status and nicotine withdrawal severity in affective and physiological response to, and recovery from, a carbon-dioxide challenge (four minutes of 10% CO2-enriched air). We found evidence that PD and nicotine withdrawal independently and interactively predict physiological panic responsivity, and recovery to a CO2 challenge, as indexed by tidal levels of expired CO2 (ETCO2). In addition, we found that smokers experiencing more nicotine withdrawal reported greater emotional distress in response to the challenge; however, during recovery from the challenge, those with PD, regardless of nicotine withdrawal severity, reported a faster reduction in anxiety.
Menstrual Cycle Phase
(Rutgers University, University of Vermont, VA Boston Healthcare System; PI: Sanjana Manikandan [honors thesis]; Advisors: Teresa Leyro, Ph.D.) This senior honors project examined the moderating effect of menstrual cycle phase on the relation between emotion dysregulation and menstrual symptoms and perceived control over anxiety-related events. We found that women high in emotion dysregulation experience greater symptom severity in the luteal phase and percieve themselves as having less control over their anxiety as compared to women that are low in emotion dysregulation or women in the follicular phase.
and Psychosocial Functioning
Role of Distress Tolerance and
Smoking Cessation Processes
(University of California, San Francisco;
PI: Teresa Leyro, Ph.D.; Mentors: Sharon M. Hall, Ph.D.
Prochaska, Ph.D.): This project was funded by a center grant
(P50-DA09253) pilot study fund. The goal was to clarify the predictive
utility of a comprehensive battery of self-report and behavioral
indices of distress tolerance (DT) in terms of quit day nicotine
withdrawal, urge to smoke and craving for cigarette, as well as quit
day success. In addition, we explored the relevance of pre to post-quit
day changes in stress-relevant hormones (e.g., cortisol and
dehydroepiandrosterone) in terms of these outcomes. After baseline
assessment, participants were instructed to make a self-quit attempt
and returned to the lab 24 hours into their attempt so that we could
assess outcomes of interest. Data collection is continuing at Rutgers
Regulation of Emotional Processes
California, San Francisco; PI: Wendy Mendes, Ph.D.;
Leyro, Ph.D. and Renee
Thompson, Ph.D.). This project seeks to examine
differences in emotion regulation processes as indexed via affect,
physiology, and unconscious processes, among healthy women in the
context of the Trier Social Stress Task (TSST). In addition,
participants were randomized to receive either neutral/negative, or
positive feedback during the (TSST) in an effort to manipulate
challenge and threat responding. Analyses are ongoing.
Distress Tolerance and Inpatient Smokers
(University of California, San Francisco: PI: Teresa
Prochaska, Ph.D.). The goal of this
investigation is to (1) examine the validity of a composite index of DT
an inpatient psychiatric sample of daily smokers; and (2) examine its
relation to psychosocial parameters (e.g., cigarettes smoked daily,
nicotine dependence, psychological functioning). Analyses are ongoing.
E-cigarette Use in Young
Adults: Motives, Co-use, and Risk
(Rutgers University; PI: Teresa Leyro, Ph.D.). In this study we will examine the (1) prevalence of ever and current e-cigarette use in a college aged sample. In addition, (2) we will explore motives for use, use expectancies, and co-use with other substances (e.g., cannabis and alcohol). Finally, (3) we will explore whether use is related to a range of demographic as well as cognitive-affective risk factors (e.g., distress tolerance). Data collection to begin in the Fall of 2015.